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LH, FSH, Test low

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Old 03-06-2006, 08:15 PM
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LH, FSH, Test low

Went to my primary care doc, bloodwork showed low norman test. He agreed to 200 mg. depot test every three weeks, no sooner. Did this for 2 months, he suggested I see a uro or endo. I saw a uro who ordered FSH, LH, Prolactin, and Total Test. He called today saying he got a verbal from the lab and my LH was almost non detectable, with low test and low FSH. He didn't have the values yet but now wants me to see and endo!!! My question is this, doesn't exogen test lower your LH and FSH? I mean for about 10 days after the depot test I felt great, then the crash came...is it necessary to see the endo...I'm sure he will want to have an mri done of my pituitary for a tumor or lesion. Also this low test has been going on for about 5 years....I feel like I'm having to educate the uro. The earliest I can get into an endo in maybe in May....thats a long time to exist with no test!!! Would test suppl. hide anthing in an mri of my pituitary??? I am just lookin for some feedback...would getting my own test cyp and hitting 100mg per week be unwise? Not wanting to cycle, just feel like a normal man....
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Old 03-07-2006, 02:05 PM
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Resident biochemist to the rescue! :)

ok.......let's see if I can make sense of all of this for you.

luteinizing hormone (LH) has a direct effect on your body's Leydig cells which cause stimulation and secretion of testosterone (T). follicle stimulating hormone (FSH) has a direct effect on your body's Sertoli cells which control sperm production. Prolactin is usually found in women and stimulates the mammary gland to produce milk aka lactation. (hence prefix "pro")

Now if your tests indicate that you have low T, LH and FSH levels, then that is a strong indicator that you are probably infertile. This probably also means you have low sex drive which is probably exacerbated by an unusually high level of prolactin. (prolactin has been linked to decreased libido)

Now to answer your question, yes, exogenous testosterone does lower your FSH and LH levels. FSH and LH are both gonadotrophins b/c they stimulate the gonads (testicles in men and ovaries in women). In the presence of exogenous testosterone, you essentially put your body into a negative feedback mechanism which tells the gonads to stop production of LH and FSH.

I can help you more if I had more info such as cycle history, any medication you may be taking, level of sexual desire, etc.
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Old 03-07-2006, 03:42 PM
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Hey thanks for the reply...ok about me. No past cycles. I am a 51 year old male. Approxiamtely 5 years ago went a male hormone clinic. Was tested for Total and Free test, both low normal. Went on a cream test, 10mg, that was compounded. 6 months later my test was in the mid range..500's. The clinic went out of business and the Dr. that took it over jacked the prices so I could not continue. No pct, didn't know what that was. Then in Oct. of 2005 I was so sluggish, fat had mounded on in 5 years, no sex drive, ed, depressed, felt like shit. Convinced my primary to test for test. He ran free and total..both low normal. In nov. 2005 I rec'd my first IM injection of 200 mg test depot. and have done so since that time every three weeks. No other drugs or anabolics. No otc supplements other than a multi vitamin. Had surgery in Jun 05 to repair torn labrum in left hip. No other health problems that i'm aware of. I'm actually pretty healthy other than the low test. Being infertile does not bother me if I am....we have had all our children. I appreciate the help....the dr's seem so fricking clueless when it comes to male hormones and andropause. What do ya think?
Quote:
Originally Posted by Pdogg310
Resident biochemist to the rescue! :)

ok.......let's see if I can make sense of all of this for you.

luteinizing hormone (LH) has a direct effect on your body's Leydig cells which cause stimulation and secretion of testosterone (T). follicle stimulating hormone (FSH) has a direct effect on your body's Sertoli cells which control sperm production. Prolactin is usually found in women and stimulates the mammary gland to produce milk aka lactation. (hence prefix "pro")

Now if your tests indicate that you have low T, LH and FSH levels, then that is a strong indicator that you are probably infertile. This probably also means you have low sex drive which is probably exacerbated by an unusually high level of prolactin. (prolactin has been linked to decreased libido)

Now to answer your question, yes, exogenous testosterone does lower your FSH and LH levels. FSH and LH are both gonadotrophins b/c they stimulate the gonads (testicles in men and ovaries in women). In the presence of exogenous testosterone, you essentially put your body into a negative feedback mechanism which tells the gonads to stop production of LH and FSH.

I can help you more if I had more info such as cycle history, any medication you may be taking, level of sexual desire, etc.
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Old 03-07-2006, 04:50 PM
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Quote:
Originally Posted by Teabagger
Hey thanks for the reply...ok about me. No past cycles. I am a 51 year old male. Approxiamtely 5 years ago went a male hormone clinic. Was tested for Total and Free test, both low normal. Went on a cream test, 10mg, that was compounded. 6 months later my test was in the mid range..500's. The clinic went out of business and the Dr. that took it over jacked the prices so I could not continue. No pct, didn't know what that was. Then in Oct. of 2005 I was so sluggish, fat had mounded on in 5 years, no sex drive, ed, depressed, felt like shit. Convinced my primary to test for test. He ran free and total..both low normal. In nov. 2005 I rec'd my first IM injection of 200 mg test depot. and have done so since that time every three weeks. No other drugs or anabolics. No otc supplements other than a multi vitamin. Had surgery in Jun 05 to repair torn labrum in left hip. No other health problems that i'm aware of. I'm actually pretty healthy other than the low test. Being infertile does not bother me if I am....we have had all our children. I appreciate the help....the dr's seem so fricking clueless when it comes to male hormones and andropause. What do ya think?
TB,

Considering that the avg adult male produces around 100 mg of T per week, I think it would be safe to say that 200 mg of HRT test every 3 weeks is NOT enough for you. Depending on your level of GnRH and how out of synch your hypothalamus-pituitary testicular axis(HPTA) is, you can do one of three things:

1) try HCG (human chorionic gonadotropin) and clomid therapy in an effort to restart your body's LH and FSH production

2) self administer 200 mg test/wk (the endocrinologist will give you 200 mg every 3 weeks and we both know that's not mathematically correct)

3) do nothing, get fat and depressed
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