The
HGH Fragment is a modified form (Figure 1) of amino acids 176-191 at the C-terminal region of the human growth hormone (
hGH).
Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the GH molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or
insulin resistance. It works by mimicking the way natural
hGH regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified
hGH. Like unmodified GH, the
HGH fragment 176-191 stimulates lipolysis and inhibits lipogenesis both in laboratory testing and in animals and humans. The
HGH fragment does not appear to affect appetite.
In laboratory tests on fat cells from rodents, pigs, dogs, and humans, the
HGH fragment released fat specifically from obese fat cells but not from lean ones, reduced new fat accumulation in all fat cells, enhanced the burning of fat. In rodents (rats and mice),
HGH fragment reduced body fat in obese animals but, enhanced fat burning without changing food consumption or inducing growth (as it does not increase
IGF levels) or any other unwanted
hGH effect.
08-18-2007, 11:44 PM
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