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IGF-1, Insulin, HGH Forum IGF-1, Insulin, and Human Growth Hormone (HGH) Discussion

General GH info...very good overview

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Old 04-27-2004, 04:13 PM
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Quote:
Originally Posted by scotty
Einstein,

Do you take your dosages in the AM? or spread throughout the day? I've been running mine at night just before bedtime and it seems to work well for me but I would love for it to work better.

Scotty
I take mine at almost the exact same times as Mallet. I will be trying a immediately before bedtime 1x/day injection for awhile. There are studies (albeit old) that suggest there is a delayed onset of suppression of endogenous GH, so that you still may get the benefit of your own nocturnal release (don't misinterpret that, perverts). I'll see how that goes. My idea by AM and early afternoon shots are based on natural GH pulses and half-life of GH and IGF-1, so that this timing should not interfere with noctural GH release, but there are studies to support both methods (dosing schedules). I'd suggest trying the AM/early afternoon split to see if you notice a difference. Cortisol peaks at these 2 times too, so there is added benefit to shooting then.
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Old 04-27-2004, 08:19 PM
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Excellent. As I've been running nights I will switch up and let you know how it goes. My doctor was fairly agnostic about it saying she has had her patients running it either way and that in every case the IGF-1 measurements were the same. She did contend though that evenings seemed to produce greater fat burning effects and mornings more of an anabolic effect. Not based on anything other than her patients and her own experience.

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Old 04-28-2004, 12:48 PM
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Quote:
Originally Posted by einstein1905
I take mine at almost the exact same times as Mallet. I will be trying a immediately before bedtime 1x/day injection for awhile. There are studies (albeit old) that suggest there is a delayed onset of suppression of endogenous GH, so that you still may get the benefit of your own nocturnal release (don't misinterpret that, perverts). I'll see how that goes. My idea by AM and early afternoon shots are based on natural GH pulses and half-life of GH and IGF-1, so that this timing should not interfere with noctural GH release, but there are studies to support both methods (dosing schedules). I'd suggest trying the AM/early afternoon split to see if you notice a difference. Cortisol peaks at these 2 times too, so there is added benefit to shooting then.
BINGO!
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Old 04-28-2004, 12:50 PM
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Are her patients suffering from dwarfism? or a burnt out pituitary? This would be hard to compare with someone (like us) who have healthy pituitaries and taking GH and it's overall effects.

Quote:
Originally Posted by scotty
Excellent. As I've been running nights I will switch up and let you know how it goes. My doctor was fairly agnostic about it saying she has had her patients running it either way and that in every case the IGF-1 measurements were the same. She did contend though that evenings seemed to produce greater fat burning effects and mornings more of an anabolic effect. Not based on anything other than her patients and her own experience.

Scotty
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Old 04-28-2004, 11:43 PM
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Quote:
Originally Posted by Mallet
Are her patients suffering from dwarfism? or a burnt out pituitary? This would be hard to compare with someone (like us) who have healthy pituitaries and taking GH and it's overall effects.

No, She is an anti-aging specialist so most of her patients are well healed guys fighting old age. She also has a few like me who are athletes and a few body builders. In most cases it will be guys who are seeing a drop-off in their pituitary function due to old age. While I'm only 38, my pituitary seems to be low functioning across the board as I am also secondary hypogonadic (that is, the hypothalimus-pituitary does not send enough signals for proper T production).

I'm presently on 2IU's per day but as I progress I will likely begin to increase that dosage periodically in conjunction with my Test and Winstrol cycles.

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Old 04-29-2004, 10:40 PM
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Well there are certainly those who will say they make excellent gains without slin, my guess is they are probably affraid of taking slin and that's there reasoning. For experimental purposes I've tried both, and found the added slin to be more effective than GH alone. However I was monitoring my BG 2 hours after administration to see how my insulin sensitivity was being inhibited, I found the need for Insulin, I also found less of a an increase in BMR taking GH alone, the added slin seem to increase my BMR slightly. Not to mention slins timing with GH and it's effects on IGF1? I think Einstein can go into greater detail on this!
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Old 04-30-2004, 02:07 AM
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Quote:
Originally Posted by Boxerblood
interesting.... but without insulin you are saying that the your BMR did raise at all or not to a significant level? I am very up to date on insulin and I have done a lot of research on it. that is why I am looking into gH now. I feel I have a grasp on insulin and now I am trying to educate myself on gH. once I have the two down, there will be no stopping me. But I was wondering, what would the effect be on a person if they did not take insulin and still have the uneffected BMR? Would the gains still be significant? Or would the insulin add that much of an effect? Just Curious....

Boxer
Insulin and GH complement each other with regards to their abilities to shuttle amino acids. GH facilitates the transport of particular amino acids, and insulin shuttles the rest....there's great synergy to be had there. Once intracellular glucose and amino acids aren't the limiting factor anymore, everything else occurs much closer to its max potential.
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Old 04-30-2004, 02:09 AM
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einstein and mallet

great advice guys, keep up the good work!
 
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Old 05-09-2004, 10:22 PM
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I think we should make this a sticky Einstein! there were alot of good questions answered after the informative read you've posted!
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Old 05-21-2004, 11:39 AM
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whats up

Quote:
Originally Posted by masswithclass
Any personal experiences would be nice. I'm getting ready to hit gh for the first time.
whats up buddy this is big jim (AKA Barndoorlats) i finally signed up and this shit is awesome. u were right lots of great info on here. Keep in touch bro.
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